Clsi M22a3 Pdf May 2026
Excessive moisture, dehydration, or frozen/melted agar. Contamination: Any visible growth or excessive bubbles. Purchasing and Access
The standard, titled "Quality Control for Commercially Prepared Microbiological Culture Media; Approved Standard—Third Edition," provides a framework for both manufacturers and laboratory users to ensure the reliability of ready-to-use culture media. Published in 2004, it serves as a consensus-based guide for maintaining quality assurance in clinical microbiology. Key Purpose and Scope clsi m22a3 pdf
The full document is available in electronic PDF format from various official standards retailers. Go to product viewer dialog for this item. CLSI M22-A3 (R2018) Excessive moisture, dehydration, or frozen/melted agar
Includes new recommendations for QC of media used to recover difficult-to-grow pathogens. Laboratory Inspection Requirements Published in 2004, it serves as a consensus-based
The primary premise of M22-A3 is to reduce the burden of redundant testing. It identifies specific media of "proven reliability" for which users do not need to perform additional retesting if the manufacturer's quality control (QC) practices meet established criteria.
An additional 27 media were added to the "exempt" list, meaning labs can bypass routine QC organism testing for these items.
The acceptable failure rate cutoff for exempting media was increased from 0.3% to 0.5% .